Small Granules (0.25-1mm)

Large Granules (1-2mm)

InterOss® Anorganic Cancellous Bone Graft Granules

InterOss® is a natural hydroxyapatite bone grafting material derived from Australia bovine bone (BSE free).

This highly purified osteoconductive material is produced from natural bone through a multi-step purification process. Its natural origin makes InterOss® chemically and structurally comparable to mineralized human bone (nanocrystalline natural apatite).

InterOss® is available in granule form. It is supplied sterile and is dedicated for single use.

The presence of a macroporous structure favors cell ingrowth, while the micropores allow the penetration of body fluids into the implant. The microporosity can also be used to manipulate resorption and dissolution rate: the greater the microporosity, the greater the degradation rate.

The pore structure and interconnected pore system of InterOss® allow the grafting material to act as a guide for body fluids, growth factors, blood vessel, bone marrow, and bone cells.

Granules

Mesopore (10 – 100μm)

Macropore (>100μm)

Micropore (<10μm)

Anorganic Bovine Bone Substitute

Bovine Origin
Safe
Biocompatible
Highly Purified
Large Inner Surface Area
Long-Term Stability
Multi-Porosity

• Storage: InterOss® should be stored in a dry, clean and well ventilated place at ambient temperature (15-25°C/59-77°F). Keep the product in aseptic conditions until use.
• Sterilization: InterOss® is sterilized using gamma irradiation. Appropriate aseptic technique should be observed in all operations. The package should be inspected prior to use to ensure that the sterile barrier has not been compromised.
• Caution: Federal (USA) law restricts this device to sale by or on the order of a licensed dentist.