Synthetic Bioceramic

Synthetic Bioceramic

Descriptions

SigmaGraft Biomaterials provides ceramic particles such as hydroxyapatite (HAp), beta-tricalcium phosphate (β-TCP), and biphasic calcium phosphate (BCP) for an application of various bone graft substitute or other medical implant applications. Custom sizes available upon request.

Hydroxyapatite (HAp)

Hydroxyapatite (HAp) is a calcium phosphate similar to the human hard tissues in morphology and composition. The chemical formula of HAp is Ca5(PO4)3(OH). Particularly, it has a hexagonal crystal structure and a Ca/P ratio of 1.67 that is identical to human bone. HAp is the most stable calcium phosphate with low solubility in physiological environments defined by temperature, pH, body fluids, etc.

*Synonyms: Calcium phosphate tribasic, calcium hydroxyapatite

Beta-tricalcium phosphate (β-TCP)

β-TCP is a biodegradable bioceramic with the chemical formula Ca3(PO4)2 with a Ca/P ratio of 1.5. β-TCP has a faster degradation rate and higher solubility than hydroxyapatite. It has a high resorption rate and is widely used to increase biocompatibility.

Biphasic calcium phosphate (BCP)

BCP generally combine two more incompatible calcium phosphates, such as the more stable HAp and the more soluble β-TCP with different compositions. BCP have been used as bone grafts, bone substitute materials, and dental materials. The mixture of HAp and β-TCP can be used to stimulate the osteogenic differentiation, increase cell adhesion, and enhance mechanical properties.

Product Specifications

Hydroxyapatite (HAp)

SKU Particle Size
SGHAPNM 200-600 nm

Beta-tricalcium phosphate (β-TCP)

SKU Particle Size
SGTCPNM 0.2-500 μm

Biphasic calcium phosphate (BCP)

SKU Particle Size
SGBCPNM 0.2-500 μm

Indications for Use

  • Fillers for reinforcing restorative glass ionomer cement (GIC) and restorative composite resin
  • Bone void fillers for orthopaedic, traumatology, spine, maxillofacial and dental surgery
  • Desensitizing agent in post teeth bleaching
  • Bone tissue engineering
  • 3D bioprinting
  • Drug and gene delivery systems
  • Remineralizing agent in toothpastes
  • Orthopedic and dental implant coating

Quality

Manufacturing high-quality biomaterials for use in medical devices is fundamental to our business. SigmaGraft® manufactures products in a controlled environment and cleanrooms and operates a quality management system according to ISO 13485.

Downloads

Inquiry

As a dedicated contract manufacturer for bioceramic materials, many of our customers have entrusted us with their unique material specifications. Fill out the information below to find out how we can manufacture the materials for you.